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Epidermal Growth FactorS
The Signal Your Skin Starts Losing Before Collagen
We talk about collagen decline.
But collagen does not disappear on its own. It waits for instructions.
Those instructions come from proteins called growth factors.
One of the most important is Epidermal Growth Factor.
When its signalling slows, skin does not just look older.
It behaves differently.
What Is Epidermal Growth Factor?
Epidermal Growth Factor is a naturally occurring protein found in healthy skin.
Its role is communication. It binds to receptors on the surface of skin cells and activates a repair response.
That response helps trigger:
Collagen production
Elastin formation
Hyaluronic acid synthesis
Surface renewal & tissue repair


Why Skin Changes After 30
As we age, natural growth factor levels decline.
At the same time, UV exposure, inflammation and oxidative stress interfere with cellular signalling.
The visible result is gradual:
Skin becomes thinner.
Elasticity softens.
Fine lines remain even when hydrated.
Recovery slows.
This is not only collagen loss.
It is signalling fatigue.
What The Research Shows
Clinical and laboratory studies on multi growth factor complexes demonstrate measurable regenerative support.

In human skin models:
- New collagen increased by 123%
- Mature collagen increased by 26%
- Elastin increased by 45 percent within 7 days
- Natural hyaluronic acid production increased by 41%
This matters because firmness is not created by one protein alone.
- Collagen provides structure.
- Elastin provides movement.
- Hyaluronic acid provides volume.
What This Means In Real Skin

In clinical practice, declining growth factor activity presents subtly.
Patients often describe their skin as:
- Less dense
- Less resilient
- More fragile
- Slower to recover

Dr Garry Cussell
Founder & Formulation Director, Rejuvaus
“In clinic, I see many patients using strong actives without improvement in structural quality. Often the issue is not intensity. It is impaired signalling. When we support communication pathways, the skin regains coordination. Structure improves more sustainably.”
The Role Of Growth FactorS In Rejuvaus
Rejuvaus does not use growth factors as a trend ingredient.
They are integrated into regenerative pathways across multiple formulas.

How Long Does It Take?
- Weeks 2 to 4
Skin feels smoother and more resilient. - Weeks 4 to 8
Improved firmness and elasticity become visible. - Weeks 8 to 12
Structural integrity improves. Skin appears denser and more supported.
Consistency produces visible change.

What Customers Notice
“My skin feels stronger before it looks dramatically different. It becomes more resilient and balanced.”
“The Growth Factor Serum improved firmness around my cheeks and eyes. It feels like my skin is rebuilding itself slowly without irritation.”


